MicroRNAs in vertebrate development

被引：313

作者：

Harfe, BD ^{[1
]}

机构：

[1] Univ Florida, Coll Med, Dept Mol Genet & Microbiol, Gainesville, FL 32610 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2005年 / 15卷 / 04期

关键词：

D O I：

10.1016/j.gde.2005.06.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The vertebrate genome contains hundreds of small non-coding 'microRNAs' that have been implicated in controlling the expression of potentially thousands of target genes. Presently, only a handful of these targets have been characterized. Recent reports of microRNA 'sensors', microRNA microarrays and the creation of vertebrates that lack all microRNA activity will aid in determining the roles played by microRNAs, and the genes that they regulate, during vertebrate development.

引用

页码：410 / 415

页数：6

共 45 条

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