MicroRNAs in vertebrate development

被引：313

作者：

Harfe, BD ^{[1
]}

机构：

[1] Univ Florida, Coll Med, Dept Mol Genet & Microbiol, Gainesville, FL 32610 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2005年 / 15卷 / 04期

关键词：

D O I：

10.1016/j.gde.2005.06.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The vertebrate genome contains hundreds of small non-coding 'microRNAs' that have been implicated in controlling the expression of potentially thousands of target genes. Presently, only a handful of these targets have been characterized. Recent reports of microRNA 'sensors', microRNA microarrays and the creation of vertebrates that lack all microRNA activity will aid in determining the roles played by microRNAs, and the genes that they regulate, during vertebrate development.

引用

页码：410 / 415

页数：6

共 45 条

[11] MicroRNA-143 regulates adipocyte differentiation
Esau, C
Kang, XL
Peralta, E
Hanson, E
Marcusson, EG
Ravichandran, LV
Sun, YQ
Koo, S
Perera, RJ
Jain, R
Dean, NM
Freier, SM
Bennett, CF
Lollo, B
Griffey, R
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (50) : 52361 - 52365
[12] MicroRNAs regulate brain morphogenesis in zebrafish
Giraldez, AJ
Cinalli, RM
Glasner, ME
Enright, AJ
Thomson, JM
Baskerville, S
Hammond, SM
Bartel, DP
Schier, AF
[J]. SCIENCE, 2005, 308 (5723) : 833 - 838
[13] Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C-elegans developmental timing
Grishok, A
Pasquinelli, AE
Conte, D
Li, N
Parrish, S
Ha, I
Baillie, DL
Fire, A
Ruvkun, G
Mello, CC
[J]. CELL, 2001, 106 (01) : 23 - 34
[14] Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags
Hubbard, SJ
Grafham, DV
Beattie, KJ
Overton, IM
McLaren, SR
Croning, MDR
Boardman, PE
Bonfield, JK
Burnside, J
Davies, RM
Farrell, ER
Francis, MD
Griffiths-Jones, S
Humphray, SJ
Hyland, C
Scott, CE
Tang, HZ
Taylor, RG
Tickle, C
Brown, WRA
Birney, E
Rogers, J
Wilson, SA
[J]. GENOME RESEARCH, 2005, 15 (01) : 174 - 183
[15] A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
Hutvágner, G
McLachlan, J
Pasquinelli, AE
Bálint, É
Tuschl, T
Zamore, PD
[J]. SCIENCE, 2001, 293 (5531) : 834 - 838
[16] RNAi:: nature abhors a double-strand
Hutvágner, G
Zamore, PD
[J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 2002, 12 (02) : 225 - 232
[17] A microRNA in a multiple-turnover RNAi enzyme complex
Hutvágner, G
Zamore, PD
[J]. SCIENCE, 2002, 297 (5589) : 2056 - 2060
[18] P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA function
Kasschau, KD
Xie, ZX
Allen, E
Llave, C
Chapman, EJ
Krizan, KA
Carrington, JC
[J]. DEVELOPMENTAL CELL, 2003, 4 (02) : 205 - 217
[19] A microRNA array reveals extensive regulation of microRNAs during brain development
Krichevsky, AM
King, KS
Donahue, CP
Khrapko, K
Kosik, KS
[J]. RNA, 2003, 9 (10) : 1274 - 1281
[20] Identification of tissue-specific microRNAs from mouse
Lagos-Quintana, M
Rauhut, R
Yalcin, A
Meyer, J
Lendeckel, W
Tuschl, T
[J]. CURRENT BIOLOGY, 2002, 12 (09) : 735 - 739

← 1 2 3 4 5 →