Sterically hindered mono(phosphines) as supporting ligands for the platinum-catalyzed hydroamination of amino alkenes

被引：61

作者：

Bender, Christopher F. ^{[1
]}

Hudson, William B. ^{[1
]}

Widenhoefer, Ross A. ^{[1
]}

机构：

[1] Duke Univ, French Family Sci Ctr, Dept Chem, Durham, NC 27708 USA

来源：

ORGANOMETALLICS | 2008年 / 27卷 / 10期

关键词：

D O I：

10.1021/om8000982

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

In an effort to develop more active catalysts for the intramolecular hydroamination of amino alkenes, we have investigated the application of sterically hindered mono(phosphines) as supporting ligands for platinum-catalyzed hydroamination. Here we demonstrate that mixtures of PtCl2 and di(tertbutyl)o-biphenyl phosphines such as P(t-Bu)(2)[2-(2-NMe2C6H4)C6H4] catalyze the hydroamination of 4-pentenyl and 5-hexenyl amines at 60-80 degrees C. This catalyst system tolerates a number of functional groups and catalyzes the cyclization of unsubstituted amino alkenes.

引用

页码：2356 / 2358

页数：3

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