Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine

被引：50

作者：

Grillo, MA ^{[1
]}

Colombatto, S ^{[1
]}

机构：

[1] Univ Turin, Dipartimento Med & Oncol Sperimentale, Sez Biochim, I-10126 Turin, Italy

来源：

AMINO ACIDS | 2004年 / 26卷 / 01期

关键词：

arginine; agmatine; arginine decarboxylase; nitric oxide; polyamines;

D O I：

10.1007/s00726-003-0030-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recently agmatine, decarboxylated arginine, has been shown to be an important biological compound in several animal tissues. This paper summarizes the known information regarding the transport of arginine, its decarboxylation and the effects of the agmatine formed mainly on NO and polyamine synthesis.

引用

页码：3 / 8

页数：6

共 47 条

[41] Regulation of intracellular polyamine biosynthesis and transport by NO and cytokines TNF-α and IFN-γ [J].

Satriano, J ;

Ishizuka, S ;

Archer, DC ;

Blantz, RC ;

Kelly, CJ .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1999, 276 (04) :C892-C899

[42]

SATRIANO J, 2002, M BIOG AM ALB TENN T, P2

[43] DIAMINE OXIDASE ACTIVITY IN A MODEL OF MULTISTEP HEPATOCARCINOGENESIS [J].

SESSA, A ;

DESIDERIO, MA ;

PERIN, A .

CANCER LETTERS, 1990, 51 (01) :75-78

[44]

SMITH MA, 1984, J REHABIL DEAF, V18, P7

[45] Endogenous nitric oxide synthase inhibitors are responsible for the L-arginine paradox [J].

Tsikas, D ;

Böger, RH ;

Sandmann, J ;

Bode-Böger, SM ;

Frölich, JC .

FEBS LETTERS, 2000, 478 (1-2) :1-3

[46] Agmatine modulates polyamine content in hepatocytes by inducing spermidine/spermine acetyltransferase [J].

Vargiu, C ;

Cabella, C ;

Belliardo, S ;

Cravanzola, C ;

Grillo, MA ;

Colombatto, S .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1999, 259 (03) :933-938

[47]

Yang XC, 1999, J PHARMACOL EXP THER, V288, P544

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