Suppression of D-galactosamine-induced rat liver injury by glycosidic flavonoids-rich fraction from green tea

被引：21

作者：

Wada, S ^{[1
]}

He, PM ^{[1
]}

Watanabe, N ^{[1
]}

Sakata, K ^{[1
]}

Sugiyama, K ^{[1
]}

机构：

[1] Shizuoka Univ, Fac Agr, Dept Appl Biol Chem, Shizuoka 4228529, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1999年 / 63卷 / 03期

关键词：

green tea; flavonoids; glycosides; liver injury; D-galactosamine;

D O I：

10.1271/bbb.63.570

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tea constituents that had a preventive effect on D-galactosamine-induced If ver injury in rats were partially purified by column chromatography from a n-butanol-soluble fraction of green tea. The fraction containing glycosidic flavonoids was found to suppress the D-galactosamine-induced increase of plasma alanine aminotransferase and aspartate aminotransferase activities. These results indicate that glycosidic flavonoids contribute, at bast in part, to the liver injury-preventive effect of green tea.

引用

页码：570 / 572

页数：3

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