In vitro anti-Helicobacter pylori activity of panaxytriol isolated from ginseng

被引：55

作者：

Bae, EA

Han, MJ

Baek, NI

Kim, DH

机构：

[1] Kyung Hee Univ, Coll Pharm, Seoul 130701, South Korea

[2] Kyung Hee Univ, Dept Food & Nutr, Seoul 130701, South Korea

[3] Kyung Hee Univ, Div Life Sci, Seoul 449701, South Korea

[4] Kyung Hee Univ, EW Pharm Res Inst, Seoul 130701, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2001年 / 24卷 / 04期

关键词：

Panax ginseng; panaxytriol; Helicobacter pylori;

D O I：

10.1007/BF02975095

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

This study investigated the effect that some polyacetylenes and protopanaxatriol, which were isolated from heated ginseng (family Araliaceae), have on inhibiting Helicobacter pylori (HP) growth. Among the compounds tested, panaxytriol was quite effective in inhibiting HP growth with an MIC of 50 mug/ml. Ginsenoside Rh1 and protopanaxatriol weakly inhibited H+/K+-ATPase from a rat stomach.

引用

页码：297 / 299

页数：3

共 14 条

[1]

RELATION BETWEEN STRUCTURE AND CYTO-TOXIC ACTIVITY OF PANAXYDOL ANALOGS AGAINST L1210-CELLS [J].