Shear force imaging of soft samples in liquid using a diving bell concept

被引：38

作者：

Koopman, M

de Bakker, BI

Garcia-Parajo, MF

van Hulst, NF

机构：

[1] Univ Twente, Fac Sci & Technol, Appl Opt Grp, NL-7500 AE Enschede, Netherlands

[2] Univ Twente, MESA Res Inst, NL-7500 AE Enschede, Netherlands

来源：

APPLIED PHYSICS LETTERS | 2003年 / 83卷 / 24期

关键词：

D O I：

10.1063/1.1634385

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We present a reliable and easy-to-use system, with a perfect analogy to a diving bell, to perform tuning fork based shear force microscopy on soft cells in liquid. Using the diving bell concept the tuning fork vibrates in air, while the tip is immersed in solution. In this way Q factors of 200 and higher in liquid are routinely obtained. The force feedback is reliable and stable over hours requiring a minimum adjustment of the set-point during imaging. With this system, tip-sample interaction forces are kept below 350 pN, enabling us to image soft dendritic cells in a buffer solution. (C) 2003 American Institute of Physics.

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收藏

页码：5083 / 5085

页数：3

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