Pyrrolidinyl-spirooxindole natural products as inspirations for the development of potential therapeutic agents

被引:2297
作者
Galliford, Chris V. [1 ]
Scheidt, Karl A. [1 ]
机构
[1] Northwestern Univ, Dept Chem, Evanston, IL 60201 USA
关键词
antitumor agents; medicinal chemistry; natural products; spirooxindoles; total synthesis;
D O I
10.1002/anie.200701342
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:8748 / 8758
页数:11
相关论文
共 158 条
[1]   INTRAMOLECULAR ALKENE ARYLATIONS FOR RAPID ASSEMBLY OF POLYCYCLIC SYSTEMS CONTAINING QUATERNARY CENTERS - A NEW SYNTHESIS OF SPIROOXINDOLES AND OTHER FUSED AND BRIDGED RING-SYSTEMS [J].
ABELMAN, MM ;
OH, T ;
OVERMAN, LE .
JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (18) :4130-4133
[2]  
AIMI N, 1978, CHEM PHARM BULL, V26, P3444
[3]  
ALI E, 1982, HETEROCYCLES, V19, P1367
[4]  
Alper P. B., 1999, ANGEW CHEM, V111, P3379
[5]  
Alper PB, 1999, ANGEW CHEM INT EDIT, V38, P3186, DOI 10.1002/(SICI)1521-3773(19991102)38:21<3186::AID-ANIE3186>3.3.CO
[6]  
2-5
[7]   Oxindoles from Phalaris coerulescens [J].
Anderton, N ;
Cockrum, PA ;
Colegate, SM ;
Edgar, JA ;
Flower, K ;
Vit, I ;
Willing, RI .
PHYTOCHEMISTRY, 1998, 48 (03) :437-439
[8]  
[Anonymous], 1999, ANGEW CHEM, V111, P2351
[9]  
Arndt H.D., 2006, ANGEW CHEM, V118, P4664
[10]   Small molecule modulators of transcription [J].
Arndt, Hans-Dieter .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (28) :4552-4560