Studies on antitussive activity of Cassia fistula (Leguminosae) leaf extract

被引:26
作者
Bhakta, T [1 ]
Mukherjee, PK [1 ]
Saha, K [1 ]
Pal, M [1 ]
Saha, BP [1 ]
机构
[1] Jadavpur Univ, Fac Engn & Technol, Dept Pharmaceut Technol, Calcutta 700032, W Bengal, India
关键词
antitussive; Cassia fistula; cough; methanol extract; sulphur dioxide;
D O I
10.1076/phbi.36.2.140.4598
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The methanal extract of Cassia fistula was investigated far its effect on a cough model induced by sulphur dioxide gas irt mice. Ir exhibited significant antitussive activity when compared with control in a dose dependent manner: The antitussive activity of the extract tvas comparable ro that of codeine phosphate, a prototypes antitussive agent. The C. fistula extract (400, 600 mg/kg, p.o.) showed maximum inhibition of cough by 44.44% and 51.85% with respect to control group.
引用
收藏
页码:140 / 143
页数:4
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