Obscuraminols, new unsaturated amino alcohols from the tunicate Pseudodistoma obscurum:: structure and absolute configuration

被引：43

作者：

Garrido, L

Zubía, E

Ortega, MJ

Naranjo, S

Salvá, J

机构：

[1] Fac Ciencias Mar, Dept Quim Organ, Cadiz 11510, Spain

[2] Univ Sevilla, Dept Anim Biol, Lab Biol Marina, E-41080 Seville, Spain

来源：

TETRAHEDRON | 2001年 / 57卷 / 21期

关键词：

marine metabolites; biologically active compounds; amino alcohols;

D O I：

10.1016/S0040-4020(01)00372-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The study of the ascidian Pseudodistoma obscurum from Tarifa Island (Cadiz, Spain) has led to the characterization of six new unsaturated 2-amino-3-ol compounds, the obscuraminols A-F. Five of them, the obscuraminols B-F, were isolated as their corresponding diacetyl derivatives. Their structures were established by spectroscopic analysis, their relative configurations by NOEDS study of oxazolidinone derivatives, and their absolute configurations by application of Mosher's method to N-acetyl derivatives. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：4579 / 4588

页数：10

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