Transcranial magnetic stimulation and epilepsy

被引:150
作者
Tassinari, CA
Cincotta, M
Zaccara, G
Michelucci, R
机构
[1] Bellaria Hosp, Dept Neurosci, Div Neurol, I-40139 Bologna, Italy
[2] Santa Maria Nuova Hosp, Neurol Unit, Florence, Italy
关键词
transcranial magnetic stimulation; epilepsy; repetitive transcranial magnetic stimulation; antiepileptic drugs; excitability; myoclonus;
D O I
10.1016/S1388-2457(03)00004-X
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Epileptic conditions are characterized by an altered balance between excitatory and inhibitory influences at the cortical level. Transcranial magnetic stimulation (TMS) provides a noninvasive evaluation of separate excitatory and inhibitory functions of the cerebral cortex. In addition, repetitive TMS (rTMS) can modulate the excitability of cortical networks. We review the different ways that TMS has been used to investigate pathophysiological mechanisms and effects of antiepileptic drugs in patients with epilepsy and epileptic myoclonus. The safety of different TMS techniques is discussed too. Finally, we discuss the therapeutic prospects of rTMS in this field. (C) 2003 International Federation of Clinical Neurophysiology. Published by Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:777 / 798
页数:22
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