Structure, biosynthesis, and properties of kurstakins, nonribosomal lipopeptides from Bacillus spp.

被引:87
作者
Bechet, Max [2 ]
Caradec, Thibault [2 ]
Hussein, Walaa [2 ]
Abderrahmani, Ahmed [3 ]
Chollet, Marlene [2 ]
Leclere, Valerie [2 ]
Dubois, Thomas [4 ]
Lereclus, Didier [4 ]
Pupin, Maude [5 ]
Jacques, Philippe [1 ,2 ]
机构
[1] Univ Lille Nord France Sci & Technol, PolytechLille IUTA, Lab Procedes Biol Genie Enzymat & Microbie ProBio, USTL,UPRES EA 1026, F-59655 Villeneuve Dascq, France
[2] Univ Lille Nord France Sci & Technol, PolytechLille IUTA, Lab Procedes Biol Genie Enzymat & Microbien ProBi, USTL,UPRES EA 1026, F-59655 Villeneuve Dascq, France
[3] Univ Sci & Technol Houari Boumed, Lab Biol Cellulaire & Mol, Fac Biol Sci, Algiers, Algeria
[4] INRA, Micalis UMR1319, F-78280 La Miniere, Guyancourt, France
[5] USTL, INRIA Lille Nord Europe, CNRS, LIFL,UMR 8022, F-59655 Villeneuve Dascq, France
关键词
Kurstakins; Lipopeptides; Bacillus cereus; Bacillus thuringiensis; NRPS; Spreading; PEPTIDE SYNTHETASES; SUBTILIS; SURFACTIN; MYCOSUBTILIN; POLYKETIDE; PREDICTION; STRAINS; DOMAINS;
D O I
10.1007/s00253-012-4181-2
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
A new family of lipopeptides produced by Bacillus thuringiensis, the kurstakins, was discovered in 2000 and considered as a biomarker of this species. Kurstakins are lipoheptapeptides displaying antifungal activities against Stachybotrys charatum. Recently, the biosynthesis mechanism, the regulation of this biosynthesis and the potential new properties of kurstakins were described in the literature. In addition, kurstakins were also detected in other species belonging to Bacillus genus such as Bacillus cereus. This mini-review gathers all the information about these promising bioactive molecules.
引用
收藏
页码:593 / 600
页数:8
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