Enhancing analogic reasoning with rTMS over the left prefrontal cortex

被引:128
作者
Boroojerdi, B
Phipps, M
Kopylev, L
Wharton, CM
Cohen, LG
Grafman, J
机构
[1] NINDS, Cognit Neurosci Sect, NIH, Bethesda, MD 20892 USA
[2] NINDS, Biostat Branch, NIH, Bethesda, MD 20892 USA
[3] NINDS, Human Cortical Physiol Sect, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1212/WNL.56.4.526
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors utilized repetitive transcranial magnetic stimulation (rTMS) in 16 normal volunteers to investigate the role of the left dorsolateral prefrontal cortex (PFC) in analogic reasoning, rTMS over the left and right PFC, over the left motor cortex, and sham stimulation over the left PFC were administered during memory and analogic reasoning conditions. rTMS over the left PFC led to a significant reduction in response times only in the analogy condition without affecting accuracy. These results indicate that the left PFC is relevant for analogic reasoning and that rTMS applied to the PFC can speed up solution time.
引用
收藏
页码:526 / 528
页数:3
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