Hydrolysis of lysergamide to lysergic acid by Rhodococcus equi A4

被引：13

作者：

Martínková, L

Kren, V

Cvak, L

Ovesná, M

Prepechalová, I

机构：

[1] Acad Sci Czech Republ, Inst Microbiol, Lab Biotransformat, CZ-14220 Prague 4, Czech Republic

[2] Galena Pharmaceut Ltd, CZ-74770 Opava Komarov, Czech Republic

来源：

JOURNAL OF BIOTECHNOLOGY | 2000年 / 84卷 / 01期

关键词：

Rhodococcus equi; amidase; lysergamide; isolysergamide; lysergic acid; isolysergic acid;

D O I：

10.1016/S0168-1656(00)00332-1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

From a mixture of lysergamide and its epimer isolysergamide, Rhodococcus equi A4 containing amidase preferentially hydrolyzed lysergamide into lysergic acid. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：63 / 66

页数：4

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