Multichannel computed tomography (MCCT) can produce extremely thin, overlapping slices. This capability allows for the acquisition of essentially isotropic data sets. These isotropic data sets can be used to produce reformatted images in any plane with virtually no loss of spatial resolution. This, imaging can be done with a single acquisition. This high-resolution technique is particularly useful in the imaging of small body parts, such as the wrist, where fine detail in essential. Drawing on clinical examples, this article reviews the use of isotropic imaging in the wrist.