Synthesis and study of an acridine substituted Troger's base:: preferential binding of the (-)-isomer to B-DNA

被引：96

作者：

Tatibouët, A

Demeunynck, M

Andraud, C

Collet, A

Lhomme, J

机构：

[1] Univ Grenoble 1, Etud Dynam & Struct Select Lab, CNRS, UMR 5616, F-38041 Grenoble, France

[2] Ecole Normale Super Lyon, CNRS, UMR 117, F-69364 Lyon 07, France

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 02期

关键词：

D O I：

10.1039/a808822e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The acridine substituted Troger's base 4 was prepared, resolved and the (-)-(7R,17R) enantiomer was shown to bind preferentially to calf-thymus B-DNA.

引用

页码：161 / 162

页数：2

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