Efficient heterogeneous racemization of secondary alcohols:: Convenient synthesis of 17α-estradiol 3-methyl ether

被引：16

作者：

Zsigmond, A

Kecskeméti, A

Bogár, K

Notheisz, F

Mernyák, E

机构：

[1] Univ Szeged, Hungarian Acad Sci, Dept Organ Chem, H-6720 Szeged, Hungary

[2] Univ Szeged, Hungarian Acad Sci, Organ Catalysis Res Grp, H-6720 Szeged, Hungary

[3] Stockholm Univ, Dept Organ Chem, SE-10691 Stockholm, Sweden

来源：

CATALYSIS COMMUNICATIONS | 2005年 / 6卷 / 08期

基金：

匈牙利科学研究基金会;

关键词：

D O I：

10.1016/j.catcom.2005.04.020

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Racemization of optically active secondary alcohols was performed on a heterogeneous Ru/Al2O3 catalyst under mild reaction conditions. The supported ruthenium catalyst is readily available, inexpensive, and capable of being recycled. It successfully racemizes secondary alcohols without any additive or cocatalyst. A convenient synthesis of an expensive steroid alcohol was developed applying the same reaction conditions. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：520 / 524

页数：5

共 20 条

[1] Catalytic racemisation of alcohols: Applications to enzymatic resolution reactions [J].