New simple chiral phosphine oxazolidine ligands:: Easy synthesis and application in the palladium-catalyzed asymmetric allylic alkylation

被引：15

作者：

Braga, AL ^{[1
]}

Sehnem, JA ^{[1
]}

Lüdtke, DS ^{[1
]}

Zeni, G ^{[1
]}

Silveira, CC ^{[1
]}

Marchi, MI ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

来源：

SYNLETT | 2005年 / 08期

关键词：

phosphines; oxazolidines; allylic alkylations;

D O I：

10.1055/s-2005-868475

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New types of chiral phosphine-oxazolidines have been easily synthesized in a straightforward one-pot process starting from optically active aminoalcohols. They were screened in the Pd-catalyzed asymmetric allylic alkylations of 1,3-diphenyl-2-propenyl acetate with dimethylmalonate. The reaction proceeds smoothly in good to excellent yields and excellent stereoselectivity was obtained (up to 97%).

引用

页码：1331 / 1333

页数：3

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