Asymmetric allylic alkylation catalyzed by palladium complexes with atropisomeric quinazolinone phosphine ligands

被引：51

作者：

Dai, XD ^{[1
]}

Virgil, S ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 07期

关键词：

3-aryl-4(3H)-quinazolinone; atropisomeric; phosphine ligands; asymmetric allylic alkylation;

D O I：

10.1016/S0040-4039(98)02599-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric inductions up to 52% ee and 87% ee have been achieved with palladium catalyzed allylic alkylation reactions using a new class of atropisomeric monodentate ((R)-1b) and chelate (2) quinazolinone phosphine ligands, respectively. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：1245 / 1248

页数：4

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