Schistosome glycans and innate immunity

被引:70
作者
Hokke, CH [1 ]
Yazdanbakhsh, M [1 ]
机构
[1] Leiden Univ, Med Ctr, Ctr Infect Dis, Dept Parasitol, NL-2300 RC Leiden, Netherlands
关键词
glycoconjugate; helminth; immunomodulation; lectin;
D O I
10.1111/j.1365-3024.2005.00781.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Schistosome glycans induce characteristic innate immune responses in the infected host. The molecular aspects of these responses, the pathways and receptors as well as the schistosome glycans and glycoconjugates involved, form an area of intense research. The relevant schistosome glycan elements and the possible mechanisms through which they act on the innate immune system are discussed in this review.
引用
收藏
页码:257 / 264
页数:8
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