Structural determination of two new sesquiterpenes biotransformed from germacrone by Mucor alternata

被引：14

作者：

Jia, Niu ^{[1
]}

Chi, M. A. Xiao ^{[1
,3
]}

Lan, Xin Xiu ^{[2
]}

Wei, Jin Hong ^{[1
]}

Dean, Guo ^{[1
]}

机构：

[1] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

[2] Beijing Vocat Coll Elect Sci & Technol, Biotechnol Appl Ctr, Beijing, Peoples R China

[3] Dalian Med Univ, Coll Pharm, Dalian 116027, Peoples R China

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 2008年 / 46卷 / 02期

关键词：

NMR; biotransformation; germacrone; sesquiterpene;

D O I：

10.1002/mrc.2148

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Eight transformed sesquiterpenes of germacrone by Mucor alternato were obtained. Their structures were characterized on the basis of spectral methods including 2D NMR. Among them, (1s, 4S, 5S, 10R)-isozedoarondiol (2)and (1R, 4S, 5S, 10R)-diepoxy-12-hydroxygermacrone (3) are new compounds. Copyright (c) 2007 John Wiley & Sons, Ltd.

引用

页码：178 / 181

页数：4

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