An expeditious synthesis of dimethyl 1-benzyl-cis-piperidine-3,5-dicarboxylate

被引：9

作者：

Danieli, B ^{[1
]}

Lesma, G ^{[1
]}

Passarella, D ^{[1
]}

Silvani, A ^{[1
]}

机构：

[1] UNIV MILAN,CNR,DIPARTIMENTO CHIM ORGAN & IND,CTR STUDIO SOSTANZE ORGAN NAT,I-20133 MILAN,ITALY

来源：

SYNTHETIC COMMUNICATIONS | 1997年 / 27卷 / 01期

关键词：

D O I：

10.1080/00397919708004806

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A mixture of dimethyl 1-benzyl-cis- and trans-piperidine-3,5-dicarboxylate is prepared in high yields from readily available starting materials, by a reliable procedure. The straightforward conversion of the mixture into the diastereomerically pure cis-isomer, a useful sigma-symmetry intermediate for alkaloid synthesis, is also described.

引用

页码：69 / 77

页数：9

共 5 条

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