Chemical and biochemical sensors based on advances in materials chemistry

The advance of materials chemistry has influenced the design of analytical sensors, especially those using spectroscopic or electrochemical methods for generating the signal. New methods of immobilizing enzymes, chromophores, and electron-transfer catalysts have resulted from initiatives in materials science. Systems based on sol-gel chemistry are especially noteworthy in this regard, but other important materials for chemical and biochemical sensors include zeolites, organic polymers, and various conducting composites. Applications cited include determinations of inorganic ions, gases, neurotransmitters, alcohols, carbohydrates, amino acids, proteins, and DNA. (C) 1999 Elsevier Science B.V. All rights reserved.