Acyclic β-amino acid catalyzed asymmetric anti-selective Mannich-type reactions

被引：53

作者：

Dziedzic, Pawel ^{[1
]}

Cordova, Armando ^{[1
]}

机构：

[1] Stockholm Univ, Dept Organ Chem, Arrhenius Lab, S-10691 Stockholm, Sweden

来源：

TETRAHEDRON-ASYMMETRY | 2007年 / 18卷 / 09期

关键词：

D O I：

10.1016/j.tetasy.2007.04.024

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The ability of a primary amine containing acyclic beta(3)-amino acids to catalyze direct asymmetric anti-selective Mannich-type reactions is presented. The reactions are generally highly diastereo- and enantioselective to give the corresponding Mannich products with up to >19:1 dr (anti/syn) and 88-99% ee. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1033 / 1037

页数：5

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