Design of a C2-symmetric chiral pyrrolidine-based amino sulfonamide:: application to anti-selective direct asymmetric Mannich reactions

被引：46

作者：

Kano, Taichi ^{[1
]}

Hato, Yoshio ^{[1
]}

Maruoka, Keiji ^{[1
]}

机构：

[1] Kyoto Univ, Dept Chem, Grad Sch Sci, Sakyo Ku, Kyoto 6068502, Japan

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 48期

关键词：

Mannich reaction; organocatalyst; tartaric acid; asymmetric synthesis;

D O I：

10.1016/j.tetlet.2006.09.147

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The anti-selective direct asymmetric Mannich reaction was found to be efficiently catalyzed by the novel pyrrolidine-based amino sulfonamide (R,R)-2 prepared from L-tartaric acid. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：8467 / 8469

页数：3

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