Regulation of Akt/PKB Ser473 phosphorylation

被引：155

作者：

Bayascas, JR ^{[1
]}

Alessi, DR ^{[1
]}

机构：

[1] Univ Dundee, MRC, Prot Phosphorylat Unit, Sch Life Sci, Dundee DD1 5EH, Scotland

来源：

MOLECULAR CELL | 2005年 / 18卷 / 02期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/j.molcel.2005.03.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For years the Akt/PKB research field has been in turmoil, trying to understand how the activating phosphorylation of Akt/PKB at Ser473 is regulated. In the past month, papers in a recent issue of Molecular Cell (Gao et al., 2005) and in Science (Sarbassov et al., 2005) may have identified the phosphatase and kinase acting on this residue.

引用

页码：143 / 145

页数：3

共 10 条

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