Au-Fe3O4 dumbbell nanoparticles as dual-functional probes

被引:446
作者
Xu, Chenjie [1 ]
Xie, Jin
Ho, Don [2 ]
Wang, Chao [1 ]
Kohler, Nathan [1 ]
Walsh, Edward G. [3 ]
Morgan, Jeffrey R. [2 ]
Chin, Y. Eugene [4 ]
Sun, Shouheng [1 ]
机构
[1] Brown Univ, Dept Chem, Providence, RI 02912 USA
[2] Brown Univ, Ctr Biomed Engn, Providence, RI 02912 USA
[3] Brown Univ, Dept Neurosci, Providence, RI 02912 USA
[4] Brown Univ, Sch Med, Dept Surg, Providence, RI 02903 USA
关键词
antibodies; magnetic properties; magnetic resonance imaging; nanoparticles; reflection imaging;
D O I
10.1002/anie.200704392
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Chemical Equation Presented) Heavy lifting: Dumbbell-shaped Au-Fe 3O4 nanoparticles are made biocompatible and suitable for attachment to A431 cells. The particles are magnetically and optically active and are useful for simultaneous magnetic and optical detection (see picture). The Au-Fe3O4 nanoparticles are promising as a new type of multifunctional probe for diagnostic and therapeutic applications. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:173 / 176
页数:4
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