Abrusoside E, a further sweet-tasting cycloartane glycoside from the leaves of Abrus precatorius

被引：27

作者：

Kennelly, EJ ^{[1
]}

Cai, LN ^{[1
]}

Kim, NC ^{[1
]}

Kinghorn, AD ^{[1
]}

机构：

[1] UNIV ILLINOIS,COLL PHARM,DEPT MED CHEM & PHARMACOGNOSY,PROGRAM COLLABORAT RES PHARMACEUT SCI,CHICAGO,IL 60612

来源：

PHYTOCHEMISTRY | 1996年 / 41卷 / 05期

基金：

美国国家卫生研究院;

关键词：

Abrus precatorius; Fabaceae; cycloartane glycoside; abrusoside E; sweet taste;

D O I：

10.1016/0031-9422(95)00792-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel cycloartane glycoside, designated abrusoside E, has been isolated from the leaves of Abrus precatorius. Its structure was determined as 3 beta-O-[beta-D-glucuronopyranosyl-(1 --> 2)-beta-D-glucopyranosyl](20S,22S)-3 beta,22-dihydroxy-9, 19-cyclolanost-24-en-26,29-dioic acid delta-lactone based upon spectroscopic methods carried out on the parent compound and its mono- and dimethyl esters. While abrusoside E was found to be only marginally sweet, the monomethyl ester proved to be more potently sweet-tasting.

引用

页码：1381 / 1383

页数：3

共 9 条

[1] MLEV-17-BASED TWO-DIMENSIONAL HOMONUCLEAR MAGNETIZATION TRANSFER SPECTROSCOPY [J].