Computational fluid dynamics of stented intracranial aneurysms using adaptive embedded unstructured grids

Recently, there has been increased interest in the use Of stents as flow diverters in the endovascular treatment of cerebral aneurysms as an alternative to surgical clipping or endovascular embolization with coils. The aim of aneurysm stenting is to block the flow into the aneurysm in order to clot the blood inside the aneurysm and effectively isolate it from the circulation and Prevent bleeding from the aneurysm. A hybrid meshing approach that combines body-fitted grids for the vessels and adaptive the stents is proposed and analyzed. This strategy simplifies considerably embedded grids for ably the geometry modeling problem and allows accurate patient-specific hemodynamic simulations with endovascular devices. This approach is compared with the traditional body-fitted approach in the case of the flow around a circular cylinder at representative Reynolds number and an idealized aneurysm model with a stent. A novel technique to map different stent designs to a given patient-specific anatomical model is presented. The methodology is demonstrated on a patient-specific hemodynamic model of an aneurysm of the internal carotid artery constructed from a 3D rotational angiogram and stented with two different stent designs. The results show that the methodology can be successfully used to model patient-specific anatomies with different stents thereby making it possible to explore different stent designs. Copyright (C) 2007 John Wiley & Sons, Ltd.