Microbiota and dietary interactions - an update to the hygiene hypothesis?

被引：98

作者：

Frei, R. ^{[1
,2
]}

Lauener, R. P. ^{[2
,3
]}

Crameri, R. ^{[1
]}

O'Mahony, L. ^{[1
]}

机构：

[1] Univ Zurich, Swiss Inst Allergy & Asthma Res, Davos, Switzerland

[2] Christine Kuhne Ctr Allergy Res & Educ, Zurich, Switzerland

[3] Hochgebirgsklin Davos Wolfgang, Davos, Switzerland

来源：

ALLERGY | 2012年 / 67卷 / 04期

基金：

瑞士国家科学基金会;

关键词：

allergy; hygiene hypothesis; immunity; microbial metabolites; REGULATORY T-CELLS; CHAIN FATTY-ACIDS; INTESTINAL IMMUNE HOMEOSTASIS; RANDOMIZED-CONTROLLED-TRIALS; CONJUGATED LINOLEIC-ACID; PLACEBO-CONTROLLED TRIAL; SCHOOL-AGE-CHILDREN; LECTIN DC-SIGN; DENDRITIC CELLS; RETINOIC-ACID;

D O I：

10.1111/j.1398-9995.2011.02783.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The dramatic increase in the incidence and severity of allergy and asthma has been proposed to be linked with an altered exposure to, and colonization by, micro-organisms, particularly early in life. However, other lifestyle factors such as diet and physical activity are also thought to be important, and it is likely that multiple environmental factors with currently unrecognized interactions contribute to the atopic state. This review will focus on the potential role of microbial metabolites in immunoregulatory functions and highlights the known molecular mechanisms, which may mediate the interactions between diet, microbiota, and protection from allergy and asthma.

引用

页码：451 / 461

页数：11

共 125 条

[1] Therapeutic manipulation of immune tolerance in allergic disease [J].

Akdis, Muebeccel ;

Akdis, Cezmi A. .

NATURE REVIEWS DRUG DISCOVERY, 2009, 8 (08) :645-660

[2] Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs [J].

Ando, Munetoshi ;

Tu, Wenjie ;

Nishijima, Ken-Ichi ;

Iijima, Shinji .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 369 (03) :878-883

[3]

[Anonymous], COCHRANE DATABASE SY

[4] Impaired T helper 2 response to aeroallergen in helminth-infected patients with asthma [J].

Araujo, MIAS ;

Hoppe, B ;

Medeiros, M ;

Alcântara, L ;

Almeida, MC ;

Schriefer, A ;

Oliveira, RR ;

Kruschewsky, R ;

Figueiredo, JP ;

Cruz, AA ;

Carvalho, EM .

JOURNAL OF INFECTIOUS DISEASES, 2004, 190 (10) :1797-1803

[5] Effects of a selection of histone deacetylase inhibitors on mast cell activation and airway and colonic smooth muscle contraction [J].

Assem, El-Sayed K. ;

Peh, Kheng H. ;

Wan, Beatrice Y. C. ;

Middleton, Brian J. ;

Dines, Jon ;

Marson, Charles M. .

INTERNATIONAL IMMUNOPHARMACOLOGY, 2008, 8 (13-14) :1793-1801

[6] Microbiotal influence on T cell subset development [J].

Atarashi, Koji ;

Umesaki, Yoshinori ;

Honda, Kenya .

SEMINARS IN IMMUNOLOGY, 2011, 23 (02) :146-153

[7] Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species [J].

Atarashi, Koji ;

Tanoue, Takeshi ;

Shima, Tatsuichiro ;

Imaoka, Akemi ;

Kuwahara, Tomomi ;

Momose, Yoshika ;

Cheng, Genhong ;

Yamasaki, Sho ;

Saito, Takashi ;

Ohba, Yusuke ;

Taniguchi, Tadatsugu ;

Takeda, Kiyoshi ;

Hori, Shohei ;

Ivanov, Ivaylo I. ;

Umesaki, Yoshinori ;

Itoh, Kikuji ;

Honda, Kenya .

SCIENCE, 2011, 331 (6015) :337-341

[8] Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease [J].

Beghdadi, Walid ;

Porcherie, Adeline ;

Schneider, Bradley S. ;

Dubayle, David ;

Peronet, Roger ;

Huerre, Michel ;

Watanabe, Takeshi ;

Ohtsu, Hiroshi ;

Louis, Jacques ;

Mecheri, Salaheddine .

JOURNAL OF EXPERIMENTAL MEDICINE, 2008, 205 (02) :395-408

[9] Probiotics for the treatment or prevention of atopic dermatitis - A review of the evidence from randomized controlled trials [J].

Betsi, Gregoria L. ;

Papadavid, Evangelia ;

Falagas, Matthew E. .

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2008, 9 (02) :93-103

[10] Dendritic Cells from Mycobacteria-Infected Mice Inhibits Established Allergic Airway Inflammatory Responses to Ragweed via IL-10-and IL-12-Secreting Mechanisms [J].

Bilenki, Laura ;

Gao, Xiaoling ;

Wang, Shuhe ;

Yang, Jie ;

Fan, Yijun ;

Han, Xiaobing ;

Qiu, Hongyu ;

Yang, Xi .

JOURNAL OF IMMUNOLOGY, 2010, 184 (12) :7288-7296

← 1 2 3 4 5 6 7 8 9 10 →