Baker's yeast mediated enantioselective synthesis of the bisabolane sesquiterpenes curcumene, turmerone, dehydrocurcumene and nuciferal

被引：69

作者：

Fuganti, C

Serra, S

Dulio, A

机构：

[1] Politecn Milan, Dipartimento Chim, CNR, Ctr Studio Sostanze Organ Nat, I-20131 Milan, Italy

[2] Perfetti Spa, I-20020 Lainate, MI, Italy

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 03期

关键词：

D O I：

10.1039/a808772e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fermenting baker's yeast converts the allylic alcohol 6 into enantiomerically pure (S)-(+)-3-(p-tolyl)butan-1-ol 7 which is a useful chiral building block for the synthesis of bisabolane sesquiterpenes. The versatility of this approach is shown in the preparation of (S)-(+)-curcumene, (S)-(+)-turmerone, (S)-(+)-dehydrocurcumene and (E,S)-(+)-nuciferal.

引用

页码：279 / 282

页数：4

共 22 条

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