Mitochondrial fission in apoptosis

被引：639

作者：

Youle, RJ ^{[1
]}

Karbowski, M ^{[1
]}

机构：

[1] Natl Inst Neurol Disorders & Stroke, Biochem Sect, Surg Neurol Branch, Natl Inst Hlth, Bethesda, MD 20892 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2005年 / 6卷 / 08期

关键词：

D O I：

10.1038/nrm1697

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Mitochondria fuse and divide continuously within cells to form a dynamic network. One of the steps in apoptosis is the fragmentation of mitochondria, and recent evidence indicates that the mitochondrial fission machinery actively participates in the process of programmed cell death.

引用

页码：657 / 663

页数：7

共 73 条

[71] The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria
Wong, ED
Wagner, JA
Gorsich, SW
McCaffery, JM
Shaw, JM
Nunnari, J
[J]. JOURNAL OF CELL BIOLOGY, 2000, 151 (02) : 341 - 352
[72] Mammalian dynamin-like protein DLP1 tubulates membranes
Yoon, Y
Pitts, KR
McNiven, MA
[J]. MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (09) : 2894 - 2905
[73] The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
Yoon, Y
Krueger, EW
Oswald, BJ
McNiven, MA
[J]. MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (15) : 5409 - 5420

← 1 2 3 4 5 6 7 8 →