The HMMTOP transmembrane topology prediction server

被引:1554
作者
Tusnády, GE
Simon, I
机构
[1] Hungarian Acad Sci, Inst Enzymol, BRC, H-1518 Budapest, Hungary
[2] Eotvos Lorand Univ, Dept Biol Phys, H-1117 Budapest, Hungary
基金
匈牙利科学研究基金会; 美国国家科学基金会;
关键词
D O I
10.1093/bioinformatics/17.9.849
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The HMMTOP transmembrane topology prediction server predicts both the localization of helical transmembrane segments and the topology of transmembrane proteins. Recently, several improvements have been introduced to the original method. Now, the user is allowed to submit additional information about segment localization to enhance the prediction power. This option improves the prediction accuracy as well as helps the interpretation of experimental results, i.e. in epitope insertion experiments.
引用
收藏
页码:849 / 850
页数:2
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