Novel dendritic ligands of chiral 1,2-diamine and their application in asymmetric hydrogenation of simple aryl ketones

被引：17

作者：

Liu, WG

Cui, X

Cun, LF

Wu, J

Zhu, J

Deng, JG ^{[1
]}

Fan, QH

机构：

[1] Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro, Chengdu 610041, Peoples R China

[2] Chinese Acad Sci, Chengdu Inst Organ Chem, Union Lab Asymmetr Synth, Chengdu 610041, Peoples R China

[3] Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Biol Chem Lab, Beijing 100080, Peoples R China

[4] Chinese Acad Sci, Grad Sch, Beijing, Peoples R China

来源：

SYNLETT | 2005年 / 10期

关键词：

chiral 1,2-diamine; dendritic ligand; ruthenium complex; asymmetric hydrogenation;

D O I：

10.1055/s-2005-869862

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel dendritic chiral vicinal diamine ligands have been synthesized and a series of dendritic Ru(BINAP)(diamine) catalysts were developed for asymmetric hydrogenation of a variety of simple aryl ketones in good catalytic activity and high enantioselectivity, as well as facile catalyst recycling. An increase of enantioselectivities was obtained by using the dendritic catalysts compared with Noyori catalysts under the same conditions in the case of several substrates. Meanwhile, a remarkable structural effect on catalytic activity and enantioselectivity, as well as reuse was observed.

引用

页码：1591 / 1595

页数：5

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