Radical medicine: treating ageing to cure disease

被引:197
作者
Finkel, T [1 ]
机构
[1] NHLBI, Cardiovasc Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1038/nrm1763
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The incidence of many diseases rises sharply with age. Although clearly separable, ageing and certain age-related diseases might share common mechanisms. Cellular metabolism and subsequent generation of reactive oxygen species might contribute both to the rate at which we age and to our susceptibility to numerous chronic diseases, therefore therapies that directly target the ageing process might provide new ways to treat human diseases.
引用
收藏
页码:971 / 976
页数:7
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