Convenient synthetic routes to 5-substituted 3-(4-methoxyphenyl)-4(1H)-quinolones

被引：13

作者：

Joseph, B

Béhard, A

Lesur, B

Guillaumet, G

机构：

[1] Univ Lyon 1, CNRS, UMR 5622, Lab Chim Organ 1, F-69622 Villeurbanne, France

[2] Univ Orleans, CNRS, UMR 6005, Inst Chim Organ & Analyt, F-45067 Orleans 2, France

[3] Cephalon France, Ctr Rech & Dev, F-94701 Maisons Alfort, France

来源：

SYNLETT | 2003年 / 10期

关键词：

quinolones; Stille reaction; Suzuki reaction; nucleophilic aromatic substitutions; aminations;

D O I：

10.1055/s-2003-40845

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Substituted 3-(4-methoxyphenyl)-4(1H)-quinolones 5-18 have been synthesised in good yields from the corresponding 3-(4-methoxyphenyl)-5-trifluoromethanesulfonate-4(1H)-quinolo- nes 4 via palladium-mediated cross-coupling reactions or aromatic nucleophilic substitution (SNAr) reactions.

引用

页码：1542 / 1544

页数：3

共 21 条

[1] THE USE OF PEARLMAN CATALYST FOR SELECTIVE N-DEBENZYLATION IN THE PRESENCE OF BENZYL ETHERS [J].