BVDV is associated with a range of economically important clinical diseases including reproductive disorders and acute fatal haemorrhagic disease in cattle industry. Vaccination is still the most important control strategy for controlling BVDV infections in many countries of the world. The existence of great genetic and antigenic diversity of BVDV isolates is very important concern for BVDV vaccine development and protective efficacy of current vaccines. In this review, the protective efficacies of the selected examples of BVDV vaccines with regard to BVDV diversity and the novel marker vaccine development studies are discussed.
机构:
USDA ARS, Virus & Pr Dis Livestock Res Unit, Natl Anim Dis Ctr, Ames, IA 50010 USAUSDA ARS, Virus & Pr Dis Livestock Res Unit, Natl Anim Dis Ctr, Ames, IA 50010 USA
机构:
USDA ARS, Natl Anim Dis Ctr, Virus & Prion Dis Livestock Res Unit, Ames, IA 50010 USAUSDA ARS, Natl Anim Dis Ctr, Virus & Prion Dis Livestock Res Unit, Ames, IA 50010 USA
机构:
USDA ARS, Virus & Pr Dis Livestock Res Unit, Natl Anim Dis Ctr, Ames, IA 50010 USAUSDA ARS, Virus & Pr Dis Livestock Res Unit, Natl Anim Dis Ctr, Ames, IA 50010 USA
机构:
USDA ARS, Natl Anim Dis Ctr, Virus & Prion Dis Livestock Res Unit, Ames, IA 50010 USAUSDA ARS, Natl Anim Dis Ctr, Virus & Prion Dis Livestock Res Unit, Ames, IA 50010 USA