EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp E-1511 and E-1625 .2. Structure determination

被引：17

作者：

Uosaki, Y

Agatsuma, T

Tanaka, T

Saitoh, Y

机构：

[1] Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Machida, Tokyo 194

来源：

JOURNAL OF ANTIBIOTICS | 1996年 / 49卷 / 11期

关键词：

D O I：

10.7164/antibiotics.49.1079

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The structures of three novel interleukin-1 beta converting enzyme inhibitors, EI-1511-3, -5 and EI-1625-2 were determined by spectroscopic methods. Their absolute configurations were also determined by analyses of the CD spectra of the inhibitors and their oxidation products with chromium trioxide.

引用

页码：1079 / 1084

页数：6

共 12 条

[1] U-56,407, A NEW ANTIBIOTIC RELATED TO ASUKAMYCIN - ISOLATION AND CHARACTERIZATION
BRODASKY, TF
STROMAN, DW
DIETZ, A
MIZSAK, S
[J]. JOURNAL OF ANTIBIOTICS, 1983, 36 (08) : 950 - 956
[2] ON THE STRUCTURE OF ALISAMYCIN, A NEW MEMBER OF THE MANUMYCIN CLASS OF ANTIBIOTICS
CHATTERJEE, S
VIJAYAKUMAR, EKS
FRANCO, CMM
BLUMBACH, J
GANGULI, BN
[J]. JOURNAL OF ANTIBIOTICS, 1993, 46 (06) : 1027 - 1030
[3] SOME ASPECTS OF THE STEREOCHEMISTRY AND BIOSYNTHESIS OF ASUKAMYCIN
CHO, HG
SATTLER, I
BEALE, JM
ZEECK, A
FLOSS, HG
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (27) : 7925 - 7928
[4] IDENTIFICATION OF RAS FARNESYLTRANSFERASE INHIBITORS BY MICROBIAL SCREENING
HARA, M
AKASAKA, K
AKINAGA, S
OKABE, M
NAKANO, H
GOMEZ, R
WOOD, D
UH, M
TAMANOI, F
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (06) : 2281 - 2285
[5] Harada N., 1983, CIRCULAR DICHROIC SP
[6] STRUCTURE OF ASUKAMYCIN, A POSSIBLE SHUNT METABOLITE FROM 3-DEHYDROQUINIC ACID IN THE SHIKIMATE PATHWAY
KAKINUMA, K
IKEKAWA, N
NAKAGAWA, A
OMURA, S
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (12) : 3402 - 3404
[7] NEW COMPOUNDS OF THE MANUMYCIN GROUP OF ANTIBIOTICS AND A FACILITATED ROUTE FOR THEIR STRUCTURE ELUCIDATION
SATTLER, I
GRONE, C
ZEECK, A
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (24) : 6583 - 6587
[8] MANUMYCIN-E, MANUMYCIN-F AND MANUMYCIN-G, NEW MEMBERS OF MANUMYCIN CLASS ANTIBIOTICS, FROM STREPTOMYCES SP
SHU, YZ
HUANG, S
WANG, RR
LAM, KS
KLOHR, SE
VOLK, KJ
PIRNIK, DM
WELLS, JS
FERNANDES, PB
PATEL, PS
[J]. JOURNAL OF ANTIBIOTICS, 1994, 47 (03) : 324 - 333
[9] TANA, 1996, J ANTIBIOT, V49, P1073
[10] EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp E-1511 and E-1625 .3. Biochemical properties of EI-1511-3, -5 and EI-1625-2
Tanaka, T
Tsukuda, E
Uosaki, Y
Matsuda, Y
[J]. JOURNAL OF ANTIBIOTICS, 1996, 49 (11) : 1085 - 1090

← 1 2 →