Brain development and assessing the supply of polyunsaturated fatty acid

被引:75
作者
Clandinin, MT [1 ]
机构
[1] Univ Alberta, Dept Agr Food & Nutr Sci, Agr Forestry Ctr 4 10, Nutr & Metab Res Grp, Edmonton, AB T6G 2P5, Canada
[2] Univ Alberta, Dept Med, Edmonton, AB, Canada
关键词
D O I
10.1007/s11745-999-0347-y
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Membrane lipids are necessary for structure and function of the developing nervous system. Rapid synthesis of brain tissue occurs during the last trimester of development of the human brain and the early postnatal weeks. This synthesis of brain structure involves the formation of complex lipids, many of which contain significant quantities of chain-elongated desaturated homologs of essential fatty acids. The present report discusses the implications of change in nutritional status on processes of brain development and metabolic events that involve lipids.
引用
收藏
页码:131 / 137
页数:7
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