Rh(III)-Catalyzed Oxidative Coupling of N-Aryl-2-aminopyridine with Alkynes and Alkenes

被引：213

作者：

Chen, Jinlei ^{[2
]}

Song, Guoyong ^{[1
]}

Pan, Cheng-Ling ^{[1
]}

Li, Xingwei ^{[1
]}

机构：

[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

[2] Jilin Univ, State Key Lab Theoret & Computat Chem, Changchun 130023, Peoples R China

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 23期

关键词：

C-H BOND; INTERNAL ALKYNES; BENZOIC-ACIDS; ACTIVATION; RH; FUNCTIONALIZATION; CLEAVAGE; COUPLING/CYCLIZATION; CARBON; BENZAMIDES;

D O I：

10.1021/ol1022596

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[RhCp*Cl-2](2) (1-2 mol %) can catalyze the oxidative coupling of N-aryl-2-aminopyridines with alkynes and arylates to give N-(2-pyridyl)indoles and N-(2-pyridyl)quinolones, respectively, using Cu(OAc)(2) as an oxidant. Coupling with styrenes gave mono- and/or disubstituted olefination products.

引用

页码：5426 / 5429

页数：4

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