Heteropoly acid-catalyzed highly efficient alkylation of 1,3-dicarbonyl compounds with benzylic and propargylic alcohols

被引：46

作者：

Yadav, J. S. ^{[1
]}

Reddy, B. V. Subba ^{[1
]}

Pandurangam, T. ^{[1
]}

Rao, K. V. Raghavendra ^{[1
]}

Praneeth, K. ^{[1
]}

Kumar, G. G. K. S. Narayana ^{[1
]}

Madavi, C. ^{[1
]}

Kunwar, A. C. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 27期

关键词：

heteropoly acids; benzylic/propargylic alcohols; 1,3-dicarbonyls; nucleophilic substitution;

D O I：

10.1016/j.tetlet.2008.04.126

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various 1,3-dicarbonyl compounds reacted readily with benzylic and propargylic alcohols in the presence of 10 mol % of phosphomolybdic acid supported on silica gel (PMA/SiO2) under mild reaction conditions to produce 2-benzylic- and 2-propargylic-1,3-dicarbonyl compounds in excellent yields and with high selectivity. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：4296 / 4301

页数：6

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