Mesenchymal stem cells as a therapeutic tool in tissue and organ regeneration

被引：28

作者：

Bajek, Anna ^{[1
]}

Olkowska, Joanna ^{[1
]}

Drewa, Tomasz ^{[1
,2
]}

机构：

[1] UMK Torun, Zaklad Inzynierii Tkankowej, Katedry Biol Med, Coll Med Ludwika Rydygiera Bydgoszczy, PL-85092 Bydgoszcz, Poland

[2] Ctr Onkol, Oddzial Urol Onkol, Bydgoszcz, Poland

来源：

POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ | 2011年 / 65卷

关键词：

bone marrow mesenchymal stem cells; tissue engineering; regenerative medicine; BONE-MARROW-CELLS; CLINICAL-APPLICATIONS; MOLECULAR-BIOLOGY; RECENT PROGRESS; STROMAL CELLS; SELF-RENEWAL; IN-VIVO; PLASTICITY; DIFFERENTIATION; TRANSDIFFERENTIATION;

D O I：

10.5604/17322693.933878

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

100103 [病原生物学]; 100218 [急诊医学];

摘要：

Tissue engineering is an interdisciplinary field that offers new opportunities for regeneration of diseased and damaged tissue with the use of many different cell types, including adult stem cells. In tissue engineering and regenerative medicine the most popular are mesenchymal stem cells (MSCs) isolated from bone marrow. Bone marrow mesenchymal stem cells are a potential source of progenitor cells for osteoblasts, chondroblasts, adipocytes, skeletal muscles and cardiomyocytes. It has also been shown that these cells can differentiate into ecto- and endodermal cells, e.g. neuronal cells, glial cells, keratinocytes and hepatocytes. The availability of autologous MSCs, their proliferative potential and multilineage differentiation capacity make them an excellent tool for tissue engineering and regenerative medicine. The aim of this publication is to present characteristic and biological properties of mesenchymal stem cells isolated from bone marrow.

引用

页码：124 / 132

页数：9

共 88 条

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