Cadherin function: Breaking the barrier

被引：25

作者：

Ishii, K

Green, KJ

机构：

[1] Northwestern Univ, Sch Med, Dept Pathol, Chicago, IL 60611 USA

[2] Northwestern Univ, Sch Med, Dept Dermatol, Chicago, IL 60611 USA

来源：

CURRENT BIOLOGY | 2001年 / 11卷 / 14期

关键词：

D O I：

10.1016/S0960-9822(01)00346-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three desmoglein isoforms collaborate with desmocollins to build the adhesive core of desmosomes. A recent study has shown that altering the ratio of desmoglein isoforms influences epidermal barrier function, suggesting distinct roles for these cadherins that extend beyond adhesion.

引用

收藏

页码：R569 / R572

页数：4

相关论文

共 29 条

[21] Distinct desmocollin isoforms occur in the same desmosomes and show reciprocally graded distributions in bovine nasal epidermis [J].

North, AJ ;

Chidgey, MAJ ;

Clarke, JP ;

Bardsley, WG ;

Garrod, DR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (15) :7701-7705

[22]

Norvell SM, 1998, J CELL SCI, V111, P1305

[23]

Nuber UA, 1996, EUR J CELL BIOL, V71, P1

[24]

NUBER UA, 1995, EUR J CELL BIOL, V66, P69

[25] IDENTIFICATION OF THE UBIQUITOUS HUMAN DESMOGLEIN, DSG2, AND THE EXPRESSION CATALOG OF THE DESMOGLEIN SUBFAMILY OF DESMOSOMAL CADHERINS [J].

SCHAFER, S ;

KOCH, PJ ;

FRANKE, WW .

EXPERIMENTAL CELL RESEARCH, 1994, 211 (02) :391-399

[26] Lack of mucosal involvement in pemphigus foliaceus may be due to low expression of desmoglein 1 [J].

Shirakata, Y ;

Amagai, M ;

Hanakawa, Y ;

Nishikawa, T ;

Hashimoto, K .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1998, 110 (01) :76-78

[27] Cadherins and their connections: adhesion junctions have broader functions [J].

Steinberg, MS ;

McNutt, PM .

CURRENT OPINION IN CELL BIOLOGY, 1999, 11 (05) :554-560

[28] Desmosomal adhesion inhibits invasive behavior [J].

Tselepis, C ;

Chidgey, M ;

North, A ;

Garrod, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (14) :8064-8069

[29] Protection against pemphigus foliaceus by desmoglein 3 in neonates. [J].

Wu, H ;

Wang, ZH ;

Yan, A ;

Lyle, S ;

Fakharzadeh, S ;

Wahl, JK ;

Wheelock, MJ ;

Ishikawa, H ;

Uitto, J ;

Amagai, M ;

Stanley, JR .

NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (01) :31-35