Diffuse optical imaging and spectroscopy, in vivo

被引:13
作者
Gandjbakhche, AH [1 ]
机构
[1] NICHHD, Lab Integrat & Med Biophys, NIH, Bethesda, MD 20892 USA
来源
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE IV PHYSIQUE ASTROPHYSIQUE | 2001年 / 2卷 / 08期
关键词
scattering; fluorescence; absorption; tomography; optical biopsy; biological tissues;
D O I
10.1016/S1296-2147(01)01251-3
中图分类号
P1 [天文学];
学科分类号
0704 ;
摘要
Based on photon migration the new goal of diffuse optical imaging is to reveal optical contrasts in the depth of biological tissues. We discuss first the origin of contrast mechanism (absorption, fluorescence and scattering) used on diffuse optical imaging and spectroscopy. Then, various experimental approaches are described based on CW, pulsed and modulated light excitation and detection. Theoretical models which provide solutions for direct and inverse problems are presented using random walk theory. Finally two studies on breast imaging and on the use of fluorescence exogeneous markers are discussed in detail. Publie par Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:1073 / 1089
页数:17
相关论文
共 63 条
[11]  
Cutler M, 1929, Surg. Gynaecol, V48, P721
[12]  
Duderstadt J. J., 1976, NUCL REACTOR ANAL
[13]   Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods [J].
Fantini, S ;
Walker, SA ;
Franceschini, MA ;
Kaschke, M ;
Schlag, PM ;
Moesta, KT .
APPLIED OPTICS, 1998, 37 (10) :1982-1989
[14]   UPCONVERTING TIME GATE FOR IMAGING THROUGH HIGHLY SCATTERING MEDIA [J].
FARIS, GW ;
BANKS, M .
OPTICS LETTERS, 1994, 19 (22) :1813-1815
[15]   A DIFFUSION-THEORY MODEL OF SPATIALLY RESOLVED, STEADY-STATE DIFFUSE REFLECTANCE FOR THE NONINVASIVE DETERMINATION OF TISSUE OPTICAL-PROPERTIES INVIVO [J].
FARRELL, TJ ;
PATTERSON, MS ;
WILSON, B .
MEDICAL PHYSICS, 1992, 19 (04) :879-888
[16]   Frequency-domain photon migration measurements of normal and malignant tissue optical properties in a human subject [J].
Fishkin, JB ;
Coquoz, O ;
Anderson, ER ;
Brenner, M ;
Tromberg, BJ .
APPLIED OPTICS, 1997, 36 (01) :10-20
[17]  
FOX RL, 1992, SJOGREN SYNDROME
[18]   Frequency-domain techniques enhance optical mammography: Initial clinical results [J].
Franceschini, MA ;
Moesta, KT ;
Fantini, S ;
Gaida, G ;
Gratton, E ;
Jess, H ;
Mantulin, WW ;
Seeber, M ;
Schlag, PM ;
Kaschke, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (12) :6468-6473
[19]   SCALING RELATIONSHIPS FOR ANISOTROPIC RANDOM-WALKS [J].
GANDJBAKHCHE, AH ;
BONNER, RF ;
NOSSAL, R .
JOURNAL OF STATISTICAL PHYSICS, 1992, 69 (1-2) :35-53
[20]   SCALING RELATIONSHIPS FOR THEORIES OF ANISOTROPIC RANDOM-WALKS APPLIED TO TISSUE OPTICS [J].
GANDJBAKHCHE, AH ;
NOSSAL, R ;
BONNER, RF .
APPLIED OPTICS, 1993, 32 (04) :504-516