One-pot cascade approach to 1,3′-bipyrrole derivatives from trisubstituted olefins with tosylmethyl-isocyanide (TosMIC)

被引:14
作者
Qiu, Fangli [1 ,2 ]
Wu, Jianwei [1 ]
Zhang, Yaohong [1 ]
Hu, Miao [1 ]
Yu, Yongping [1 ]
机构
[1] Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Zhejiang, Peoples R China
[2] Taizhou Univ, Coll Pharmaceut & Chem Engn, Taizhou 317000, Peoples R China
基金
中国国家自然科学基金;
关键词
1.3'-Bipyrrole; Toluenesulfonyl-methyl isocyanide; (TosMIC); Trisubstituted olefins; SULFONYLMETHYL ISOCYANIDES; (+/-)-MARINOPYRROLE; 3-NITROPYRROLES; MARINOPYRROLE; CHEMISTRY; PYRROLES;
D O I
10.1016/j.tetlet.2011.11.076
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel and effective route for the synthesis of 1,3'-bipyrrole derivatives by multisubstituted olefins with TosMIC was developed. Moreover, the synthetic protocol was simple and the reaction conditions were mild. A possible mechanism was proposed. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:446 / 448
页数:3
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