Gene therapy for tissue repair and regeneration

被引：70

作者：

Bonadio, J

Goldstein, SA

Levy, RJ

机构：

[1] Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Sch Med, Dept Surg, Orthopaed Res Labs,Sect Orthopaed Surg, Ann Arbor, MI 48109 USA

[3] Childrens Hosp Philadelphia, Abramson Pediat Res Ctr, Philadelphia, PA 19104 USA

来源：

ADVANCED DRUG DELIVERY REVIEWS | 1998年 / 33卷 / 1-2期

关键词：

fracture repair; cytokine; plasmid gene transfer; granulation tissue; fibroblast; gene activated matrix;

D O I：

10.1016/S0169-409X(98)00020-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review presents a current overview of the discipline of human gene therapy. In addition, a gene therapy method is described in which plasmid genes are transferred from a structural matrix carrier into fresh wound sites so as to enhance tissue repair and regeneration. The potential to develop a gene therapy for bone regeneration is discussed in detail. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：53 / 69

页数：17

共 185 条

[41] Nonviral strategies for gene therapy [J].

Felgner, PL .

SCIENTIFIC AMERICAN, 1997, 276 (06) :102-106

[42] Receptor-mediated gene transfer into macrophages [J].

Ferkol, T ;

Perales, JC ;

Mularo, F ;

Hanson, RW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (01) :101-105

[43] PARATHYROID-HORMONE FOR THE PREVENTION OF BONE LOSS INDUCED BY ESTROGEN DEFICIENCY [J].

FINKELSTEIN, JS ;

KLIBANSKI, A ;

SCHAEFER, EH ;

HORNSTEIN, MD ;

SCHIFF, I ;

NEER, RM .

NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (24) :1618-1623

[44] A RANDOMIZED COMPARISON OF CORONARY-STENT PLACEMENT AND BALLOON ANGIOPLASTY IN THE TREATMENT OF CORONARY-ARTERY DISEASE [J].

FISCHMAN, DL ;

LEON, MB ;

BAIM, DS ;

SCHATZ, RA ;

SAVAGE, MP ;

PENN, I ;

DETRE, K ;

VELTRI, L ;

RICCI, D ;

NOBUYOSHI, M ;

CLEMAN, M ;

HEUSER, R ;

ALMOND, D ;

TEIRSTEIN, PS ;

FISH, RD ;

COLOMBO, A ;

BRINKER, J ;

MOSES, J ;

SHAKNOVICH, A ;

HIRSHFELD, J ;

BAILEY, S ;

ELLIS, S ;

RAKE, R ;

GOLDBERG, S .

NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (08) :496-501

[45] NEOCARTILAGE FORMATION INVITRO AND INVIVO USING CELLS CULTURED ON SYNTHETIC BIODEGRADABLE POLYMERS [J].

FREED, LE ;

MARQUIS, JC ;

NOHRIA, A ;

EMMANUAL, J ;

MIKOS, AG ;

LANGER, R .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1993, 27 (01) :11-23

[46] BIODEGRADABLE POLYMER SCAFFOLDS FOR TISSUE ENGINEERING [J].

FREED, LE ;

VUNJAKNOVAKOVIC, G ;

BIRON, RJ ;

EAGLES, DB ;

LESNOY, DC ;

BARLOW, SK ;

LANGER, R .

BIO-TECHNOLOGY, 1994, 12 (07) :689-693

[47] JOINT RESURFACING USING ALLOGRAFT CHONDROCYTES AND SYNTHETIC BIODEGRADABLE POLYMER SCAFFOLDS [J].

FREED, LE ;

GRANDE, DA ;

LINGBIN, Z ;

EMMANUAL, J ;

MARQUIS, JC ;

LANGER, R .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1994, 28 (08) :891-899

[48] CULTIVATION OF CELL-POLYMER CARTILAGE IMPLANTS IN BIOREACTORS [J].

FREED, LE ;

VUNJAKNOVAKOVIC, G ;

LANGER, R .

JOURNAL OF CELLULAR BIOCHEMISTRY, 1993, 51 (03) :257-264

[49] PERCUTANEOUS TRANSLUMINAL IN-VIVO GENE-TRANSFER BY RECOMBINANT ADENOVIRUS IN NORMAL PORCINE CORONARY-ARTERIES, ATHEROSCLEROTIC ARTERIES, AND 2 MODELS OF CORONARY RESTENOSIS [J].

FRENCH, BA ;

MAZUR, W ;

ALI, NM ;

GESKE, RS ;

FINNIGAN, JP ;

RODGERS, GP ;

ROBERTS, R ;

RAIZNER, AE .

CIRCULATION, 1994, 90 (05) :2402-2413

[50] Human gene therapy - An immature genie, but certainly out of the bottle [J].

Friedmann, T .

NATURE MEDICINE, 1996, 2 (02) :144-147

← 1 2 3 4 5 6 7 8 9 10 →