Alternatives to vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections

被引：141

作者：

Micek, Scott T. ^{[1
]}

机构：

[1] Barnes Jewish Hosp, Dept Pharm, St Louis, MO 63110 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2007年 / 45卷

关键词：

D O I：

10.1086/519471

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Vancomycin remains the reference standard for the treatment of systemic infection caused by methicillin-resistant Staphylococcus aureus ( MRSA). However, as a result of limited tissue distribution, as well as the emergence of isolates with reduced susceptibility and in vitro resistance to vancomycin, the need for alternative therapies that target MRSA has become apparent. New treatment options for invasive MRSA infections include linezolid, daptomycin, tigecycline, and quinupristin/ dalfopristin. Additionally, a number of new anti- MRSA compounds are in development, including novel glycopeptides ( dalbavancin, telavancin, and oritavancin), ceftobiprole, and iclaprim. The present article will review clinical issues surrounding the newly marketed and investigational agents with activity against MRSA.

引用

页码：S184 / S190

页数：7

共 44 条

[11]

Cruciani M, 1996, J ANTIMICROB CHEMOTH, V38, P865

[12] Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus [J].

Diep, BA ;

Gill, SR ;

Chang, RF ;

Phan, TH ;

Chen, JH ;

Davidson, MG ;

Lin, F ;

Lin, J ;

Carleton, HA ;

Mongodin, EF ;

Sensabaugh, GF ;

Perdreau-Remington, F .

LANCET, 2006, 367 (9512) :731-739

[13] Emerging options for treatment of invasive, multidrug-resistant Staphylococcus aureus infections [J].

Drew, Richard H. .

PHARMACOTHERAPY, 2007, 27 (02) :227-249

[14] Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus [J].

Fowler, Vance G., Jr. ;

Boucher, Helen W. ;

Corey, G. Ralph ;

Abrutyn, Elias ;

Karchmer, Adolf W. ;

Rupp, Mark E. ;

Levine, Donald P. ;

Chambers, Henry F. ;

Tally, Francis P. ;

Vigliani, Gloria A. ;

Cabell, Christopher H. ;

Link, Arthur Stanley ;

DeMeyer, Ignace ;

Filler, Scott G. ;

Zervos, Marcus ;

Cook, Paul ;

Parsonnet, Jeffrey ;

Bernstein, Jack M. ;

Price, Connie Savor ;

Forrest, Graeme N. ;

Faetkenheuer, Gerd ;

Gareca, Marcelo ;

Rehm, Susan J. ;

Brodt, Hans Reinhardt ;

Tice, Alan ;

Cosgrove, Sara E. .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (07) :653-665

[15] High-dose vancomycin therapy for methicillin-resistant Staphylococcus aureus infections -: Efficacy and toxicity [J].

Hidayat, Levita K. ;

Hsu, Donald I. ;

Quist, Ryan ;

Shriner, Kimberly A. ;

Wong-Beringer, Annie .

ARCHIVES OF INTERNAL MEDICINE, 2006, 166 (19) :2138-2144

[16] Linezolid reduces length of stay and duration of intravenous treatment compared with vancomycin for complicated skin and soft tissue infections due to suspected or proven methicillin-resistant Staphylococcus aureus (MRSA) [J].

Itani, KMF ;

Weigelt, J ;

Li, JZ ;

Duttagupta, S .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2005, 26 (06) :442-448

[17] Randomized, double-blind comparison of once-weekly dalbavancin versus twice-daily linezolid therapy for the treatment of complicated skin and skin structure infections [J].

Jauregui, LE ;

Babazadeh, S ;

Seltzer, E ;

Goldberg, L ;

Krievins, D ;

Frederick, M ;

Krause, D ;

Satilovs, I ;

Endzinas, Z ;

Breaux, J ;

O'Riordan, W .

CLINICAL INFECTIOUS DISEASES, 2005, 41 (10) :1407-1415

[18] Predictors of mortality for methicillin-resistant Staphylococcus aureus health-care-associated pneumonia -: Specific evaluation of vancomycin pharmacokinetic indices [J].

Jeffres, Meghan N. ;

Isakow, Warren ;

Doherty, Joshua A. ;

McKinnon, Peggy S. ;

Ritchie, David J. ;

Micek, Scott T. ;

Kollef, Marin H. .

CHEST, 2006, 130 (04) :947-955

[19]

Kanafani Zeina A, 2006, Expert Rev Anti Infect Ther, V4, P743, DOI 10.1586/14787210.4.5.743

[20] ANALYSIS OF VANCOMYCIN ENTRY INTO PULMONARY LINING FLUID BY BRONCHOALVEOLAR LAVAGE IN CRITICALLY ILL PATIENTS [J].

LAMER, C ;

DEBECO, V ;

SOLER, P ;

CALVAT, S ;

FAGON, JY ;

DOMBRET, MC ;

FARINOTTI, R ;

CHASTRE, J ;

GIBERT, C .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1993, 37 (02) :281-286

← 1 2 3 4 5 →