Silver-Catalyzed Intramolecular Aminofluorination of Activated Allenes

被引：121

作者：

Xu, Tao ^{[1
]}

Mu, Xin ^{[1
]}

Peng, Haihui ^{[1
]}

Liu, Guosheng ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 35期

基金：

中国国家自然科学基金;

关键词：

allenes; aminofluorination; fluorinated heterocycles; oxidation; silver; ORGANOMETALLIC COMPOUNDS; THERMAL-DECOMPOSITION; MEDIATED FLUORINATION; VINYLIC COPPER(I); AMINO ALLENES; ACIDS; HETEROCYCLES; CYCLIZATION; STANNANES; FLUORIDES;

D O I：

10.1002/anie.201103225

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A nice combination: The intramolecular oxidative aminofluorination of allenes using silver catalysis and FN(SO2Ph)2 as the fluorinating reagent has been developed. This reaction represents an efficient method for the synthesis of various 4-fluoro-2,5-dihydropyrrole compounds. Further transformation provided the corresponding fluorinated pyrrole derivatives in good yields (see scheme). © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：8176 / 8179

页数：4

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