The Tol2 transposable element of the medaka fish:: an active DNA-based element naturally occurring in a vertebrate genome

被引:22
作者
Koga, A [1 ]
Hori, H [1 ]
机构
[1] Nagoya Univ, Grad Sch Sci, Div Biol Sci, Nagoya, Aichi 4648602, Japan
关键词
D O I
10.1266/ggs.76.1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several DNA-based transposable elements are known to be present in vertebrate genomes, but few of them have been demonstrated to be active. The Tol2 element of the medaka fish is one such element and, therefore, is potentially useful for developing a gene tagging system and other molecular biological tools applicable to vertebrates. Towards this goal, analyses of the element at the molecular, cellular and population levels are in progress. Results so far obtained are described here.
引用
收藏
页码:1 / 8
页数:8
相关论文
共 58 条
[31]   Homogeneity in the structure of the medaka fish transposable element Tol2 [J].
Koga, A ;
Hori, H .
GENETICAL RESEARCH, 1999, 73 (01) :7-14
[32]   Transposable element in fish [J].
Koga, A ;
Suzuki, M ;
Inagaki, H ;
Bessho, Y ;
Hori, H .
NATURE, 1996, 383 (6595) :30-30
[33]   Amino acid sequence of a putative transposase protein of the medaka fish transposable element Tol2 deduced from mRNA nucleotide sequences [J].
Koga, A ;
Suzuki, M ;
Maruyama, Y ;
Tsutsumi, M ;
Hori, H .
FEBS LETTERS, 1999, 461 (03) :295-298
[34]   Insertion of a novel transposable element in the tyrosinase gene is responsible for an albino mutation in the medaka fish, Oryzias latipes [J].
Koga, A ;
Inagaki, H ;
Bessho, Y ;
Hori, H .
MOLECULAR & GENERAL GENETICS, 1995, 249 (04) :400-405
[35]   Discovery of amphibian Tc1-like transposon families [J].
Lam, WL ;
Seo, P ;
Robison, K ;
Virk, S ;
Gilbert, W .
JOURNAL OF MOLECULAR BIOLOGY, 1996, 257 (02) :359-366
[36]   Active transposition in zebrafish [J].
Lam, WL ;
Lee, TS ;
Gilbert, W .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (20) :10870-10875
[37]   HORIZONTAL TRANSMISSION, VERTICAL INACTIVATION, AND STOCHASTIC LOSS OF MARINER-LIKE TRANSPOSABLE ELEMENTS [J].
LOHE, AR ;
MORIYAMA, EN ;
LIDHOLM, DA ;
HARTL, DL .
MOLECULAR BIOLOGY AND EVOLUTION, 1995, 12 (01) :62-72
[38]   Characterization of the transposition pattern of the Ac element in Arabidopsis thaliana using endonuclease I-SceI [J].
Machida, C ;
Onouchi, H ;
Koizumi, J ;
Hamada, S ;
Semiarti, E ;
Torikai, S ;
Machida, Y .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (16) :8675-8680
[39]  
MCCLINTOCK B, 1948, CARNEGIE I WASH, V47, P155
[40]   A TRANSPOSABLE ELEMENT INSERTED JUST 5' TO A DROSOPHILA GLUE PROTEIN GENE ALTERS GENE-EXPRESSION AND CHROMATIN STRUCTURE [J].
MCGINNIS, W ;
SHERMOEN, AW ;
BECKENDORF, SK .
CELL, 1983, 34 (01) :75-84