Cell-cycle regulation in immunity, tolerance and autoimmunity

被引:51
作者
Balomenos, D [1 ]
Martínez-A, C [1 ]
机构
[1] CSIC, Ctr Nacl Biotecnol, Dept Immunol & Oncol, E-28049 Madrid, Spain
来源
IMMUNOLOGY TODAY | 2000年 / 21卷 / 11期
关键词
D O I
10.1016/S0167-5699(00)01748-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To trigger nn effective immune response, lymphocytes must proliferate. In addition to their direct involvement in cell-cycle progression, cell-cycle regulators might thus control immune functions. Recent evidence suggests that these regulators are essential for T-cell function; we argue that their study will provide cities for dissecting anergy and tolerance mechanisms, as well as for intervention in autoimmune diseases.
引用
收藏
页码:551 / 555
页数:5
相关论文
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